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王士維(Wang, Shih-Wei)
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職稱 |
專任教授兼所長/Ph.D. |
主要學歷 |
台灣大學藥理學研究所博士
台灣大學藥理學研究所碩士
高雄醫學大學藥學系學士 |
主要經歷 |
總務處總務長(2017-2020)
醫學系副教授(2015-2019)
學務處課外活動組組長(2012-2013)
學務處生活輔導組組長(2011-2012)
醫學系助理教授(2009-2015)
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現職 |
馬偕醫學院生物醫學研究所 專任教授兼所長(2020/01~迄今)
馬偕醫學院醫學系合聘教授 |
教學專長 |
- 藥理學
- 藥效藥理評估
- 癌症治療學
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研究專長 |
- 腫瘤微環境(包含: 血管新生、淋巴管新生及癌轉移)的調控因子及訊息傳遞研究。
- 以血管新生抑制劑為主之抗癌藥物研發及作用機轉研究。
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學術期刊 | - Yu-Ching Huang, Wei-Cheng Chen, Chen-Lin Yu, Ting-Kuo Chang, Augusta I-Chin Wei, Tsung-Ming Chang, Ju-Fang Liu, Shih-Wei Wang*. FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression.. BIOCHEMICAL PHARMACOLOGY. Vol.218:e115853. Dec. 2023. (SCI/SCIE)
- Chen-Lin Yu, Yu-Wei Lai, Jih-Jung Chen, Jie-Jen Lee, Tsung-Hsien Chou, Chen-Chen Huang, Shih-Chia Liu, Guang-Wei Chen, Chung-Hsin Tsai, Shih-Wei Wang*. Cryptocaryone induces apoptosis in human hepatocellular carcinoma cells by inhibiting aerobic glycolysis through Akt and c-Src signaling pathways. JOURNAL OF FOOD AND DRUG ANALYSIS. Vol.31-No.4:696-710. Dec. 2023. (SCI/SCIE)
- Chih-Peng Lin, Shu-Hui Wu, Tzu-Yin Lin, Chia-Hui Chu, Leu-Wei Lo, Ching-Chuan Kuo, Jang-Yang Chang, Szu-Chun Hsu, Bor-Sheng Ko, Ming Yao, Jong-Kai Hsiao, Shih-Wei Wang, Dong-Ming Huang. Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death. Pharmacological Research. Vol.197:e106945. Nov. 2023. (SCI/SCIE)
- Ho-Cheng Wu, Lung-Lin Shiu, Shih-Wei Wang, Chia-Ying Huang, Tzong-Huei Lee, Ping-Jyun Sung, Yueh-Hsiung Kuo. Anti-Lymphangiogenic Terpenoids from the Heartwood of Taiwan Juniper, Juniperus chinensis var. tsukusiensis. Plants-Basel. Vol.12-No.22:e3828. Nov. 2023. (SCI/SCIE)
- Wen-Chun Sun, Chia-Liang Lin, Tzong-Huei Lee, Chia-Hao Chang, Ann-Zhi Ong, Yen-Hsiu Yeh, Chen-Lin Yu, Guang-Wei Chen, Yi-Hsien Hsieh, Shih-Wei Wang *. Critical role of heme oxygenase-1 in chaetoglobosin A by triggering reactive oxygen species mediated mitochondrial apoptosis in colorectal cancer. Free Radical Biology and Medicine. Vol.208:833-845. Nov. 2023. (SCI/SCIE)
- Chia-Hao Chang, George Hsiao, Shih-Wei Wang, Juei-Yu Yen, Shu-Jung Huang, Wei-Chiung Chi, Tzong-Huei Lee. Chemical constituents from the medicinal herb-derived fungus Chaetomium globosum Km1226. Botanical Studies. Vol.64-No.1:e34. Nov. 2023. (SCI/SCIE)
- Yu-Wei Lai, Shih-Wei Wang, Chia-Liang Lin, Shiou-Sheng Chen, Kuan-Hung Lin, Yen-Tung Lee, Wei-Cheng Chen, Yi-Hsien Hsieh. Asiatic acid exhibits antimetastatic activity in human prostate cancer cells by modulating the MZF-1/Elk-1/Snail signaling axis.. EUROPEAN JOURNAL OF PHARMACOLOGY. Vol.951:e175770. Jul. 2023. (SCI/SCIE)
- Huang CL, Achudhan D, Liu PI, Lin YY, Liu SC, Guo JH, Liu CL, Wu CY, Wang SW, Tang CH. Visfatin upregulates VEGF-C expression and lymphangiogenesis in esophageal cancer by activating MEK1/2-ERK and NF-κB signaling. Aging-US. Vol.15-No.11:4774-4793. Jun. 2023. (SCI/SCIE) ( SDGs3, SDGs4)
- An-Sheng Lee, Yen-Ling Sung, Szu-Hua Pan, Kuo-Tzu Sung, Cheng-Huang Su, Shiao-Li Ding, Ying-Jui Lu, Chin-Ling Hsieh, Yun-Fang Chen, Chuan-Chuan Liu, Wei-Yu Chen, Xuan-Ren Chen, Fa-Po Chung, Shih-Wei Wang, Che-Hong Chen, Daria Mochly-Rosen, Chung-Lieh Hung, Hung-I Yeh, Shien-Fong Lin. A Common East Asian aldehyde dehydrogenase 2*2 variant promotes ventricular arrhythmia with chronic light-to-moderate alcohol use in mice. Communications Biology. Vol.6-No.1:e610. Jun. 2023. (SCI/SCIE)
- Cong-Min Peng, Shih-Wei Wang, Yi-Lin Hwang, Wen-Chun Sun, Li-Pin Chiu, Yi-Ting Liu, Yu-Wei Lai, Hsueh-Yun Lee. CuI-mediated synthesis of 1-aryl-5,6,7-trimethoxybenzimidazoles as potent antitubulin agents. RSC ADVANCES. Vol.13(22):e14878. May. 2023. (SCI/SCIE)
- Sunny Li-Yun Chang, Chiang-Wen Lee, Chen-Yu Yang, Zih-Chan Lin, Kuo-Ti Peng, Shih-Chia Liu, Shih-Wei Wang, Hsiao-Chi Tsai, Yi-Chin Fong, Chao-Yang Lai, Yuan-Li Huang, Chun-Hao Tsai, Chih-Yuan Ko, Ju-Fang Liu, Chih-Hsin Tang. IOX-1 suppresses metastasis of osteosarcoma by upregulating histone H3 lysine trimethylation. BIOCHEMICAL PHARMACOLOGY. Vol.210:e115472. Apr. 2023. (SCI/SCIE) ( SDGs3, SDGs4, SDGs9)
- Tzu-Yi Ke, Shih-Wei Wang, Shu-Rong Chen, Dong-Ming Huang, Yun-Sheng Lin, Tsong-Long Hwang, Wen-Chun Sun, Yuan-Bin Cheng. Alkaloids and Polyacetylenes from Hippobroma longiflora with Antiangiogenesis Properties. Journal of Natural Products. Vol.86-No.4:719-729. Apr. 2023. (SCI/SCIE)
- Liang-Wei Lin, Shih-Wei Wang, Wei-Chien Huang, Thanh Kieu Huynh, Chao-Yang Lai, Chih-Yuan Ko, Yi-Chin Fong, Jie-Jen Lee, Shun-Fa Yang, Chih-Hsin Tang. Melatonin Inhibits VEGF-Induced Endothelial Progenitor Cell Angiogenesis in Neovascular Age-Related Macular Degeneration. Cells. Vol.12-No.5:e799. Mar. 2023. (SCI/SCIE)
- Po-I Liu, Ya-Jing Jiang, An-Chen Chang, Chang-Lun Huang, Yi-Chin Fong, Jeng-Hung Guo, Chun-Lin Liu, Shih-Wei Wang, Ju-Fang Liu, Sunny Li-Yu Chang, Chih-Hsin Tang. ANGPTL2 promotes VEGF-A synthesis in human lung cancer and facilitates lymphangiogenesis.. Aging-US. Vol.15-No.5:1652-1667. Mar. 2023. (SCI/SCIE)
- Shu-Rong Chen, Shih-Wei Wang, Ching-Yeu Chen, Tzu-Yi Ke, Jue-Jun Lin, Tsong-Long Hwang, Yi-Ting Huang, Yu-Ching Huang, Yuan-Bin Cheng. Additional Azaphilones from the Marine Algae-Derived Fungus Penicillium sclerotiorum with Anti-angiogenic Activity. Bulletin of the Chemical Society of Japan. Vol.96-No.1:1-7. Jan. 2023. (SCI/SCIE)
- Hsi HY, Wang SW, Cheng CH, Pang KL, Leu JY, Chang SH, Lee YT, Kuo YH, Huang CY, Lee TH*. Chemical Constituents and Anti-Angiogenic Principles from a Marine Algicolous Penicillium sumatraense SC29. MOLECULES. Vol.27-No.24:e8940. Dec. 2022. (SCI/SCIE)
- Song CY, Chang SL, Lin CY, Tsai CH, Yang SY, Fong YC, Huang YW, Wang SW, Chen WC*, Tang CH*. Visfatin-Induced Inhibition of miR-1264 Facilitates PDGF-C Synthesis in Chondrosarcoma Cells and Enhances Endothelial Progenitor Cell Angiogenesis. Cells. Vol.11-No.21:e3470. Nov. 2022. (SCI/SCIE)
- Chen HL, Lo YH, LIN C L, Lee TH, Leung W, Wang SW, Lin IP, Lin MY, Lee CH*. Trichodermin inhibits the growth of oral cancer through apoptosis-induced mitochondrial dysfunction and HDAC-2-mediated signaling.. BIOMEDICINE & PHARMACOTHERAPY. Vol.153:e113351. Sep. 2022. (SCI/SCIE)
- Wu HC, Chen YC, Hsieh CL, Hsiao G, Wang SW, Cheng MJ, Chao CY, Lee TH*, Kuo YH*. Chemical constituents and their anti-neuroinflammatory activities from the bark of Taiwan incense cedar, Calocedrus formosana. PHYTOCHEMISTRY. Vol.204:e113347. Aug. 2022. (SCI/SCIE)
- Lu CC, Tsai HC, Yang DY, Wang SW, Tsai MH, Hua CH, Chen KJ, Chen MYC, Lien MY, Tang CH*. The Chemokine CCL4 Stimulates Angiopoietin-2 Expression and Angiogenesis via the MEK/ERK/STAT3 Pathway in Oral Squamous Cell Carcinoma. Biomedicines. Vol.10-No.7:e1612. Jul. 2022. (SCI/SCIE)
- Yu CL, Lee HL, Yang SF, Wang SW, Lin CP, Hsieh YH*, Chiou HL*. Protodioscin Induces Mitochondrial Apoptosis of Human Hepatocellular Carcinoma Cells Through Eliciting ER Stress-Mediated IP3R Targeting Mfn1/Bak Expression. Journal of Hepatocellular Carcinoma. Vol.9:327-341. Apr. 2022. (SCI/SCIE)
- Tai HC, Wang SW, Swain S, Lin LW, Tsai HC, Liu SC, Wu HC, Guo JH, Liu CL, Lai YW, Lin TH, Yang SF, Tang CH*. Melatonin suppresses the metastatic potential of osteoblastic prostate cancers by inhibiting integrin α 2 β 1 expression. JOURNAL OF PINEAL RESEARCH. Vol.72-No.3:e12793. Apr. 2022. (SCI/SCIE)
- Chen WC, Wang SW, Li CW, Lin HR, Yang CS, Chu YC, Lee TH, Chen JJ*. Comparison of Various Solvent Extracts and Major Bioactive Components from Portulaca oleracea for Antioxidant, Anti-Tyrosinase, and Anti-α-Glucosidase Activities. Antioxidants. Vol.11-No.2:e398. Feb. 2022. (SCI/SCIE)
- Achudhan D, Liu SC, Lin YY, Lee HP, Wang SW, Huang WC, Wu YC, Kuo YH, Tang CH*. Antcin K inhibits VEGF-dependent angiogenesis in human rheumatoid arthritis synovial fibroblasts. Journal of Food Biochemistry. Vol.46-No.1:e14022. Jan. 2022. (SCI/SCIE)
- Huang TF, Wang SW, Lai YW, Liu SC, Chen YJ, Hsueh TY, Lin CC, Lin CH, Chung CH. 4-Acetylantroquinonol B Suppresses Prostate Cancer Growth and Angiogenesis via a VEGF/PI3K/ERK/mTOR-Dependent Signaling Pathway in Subcutaneous Xenograft and In Vivo Angiogenesis Models. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Vol.23-No.3:e1446. Jan. 2022. (SCI/SCIE)
- Safwan S, Wang SW, Hsiao G, Hsiao SW, Hsu SJ, Lee TH*, Lee CK*. New Trichothecenes Isolated from the Marine Algicolous Fungus Trichoderma brevicompactum. Marine Drugs. Vol.20-No.2:e80. Jan. 2022. (SCI/SCIE)
- Tzong-Huei Lee, Chin-Lin Hsieh, Ho-Cheng Wu, Shih-Wei Wang, Chen-Lin Yu, George Hsiao, Ming-Jen Cheng, Wen-Tsong Hsieh, Yueh-Hsiung Kuo. Anti-lymphangiogenic diterpenes from the bark of Calocedrus macrolepis var. formosana. JOURNAL OF FOOD AND DRUG ANALYSIS. Vol.29-No.4:606-621. Dec. 2021. (SCI/SCIE)
- SzuLee, Shih-WeiWang, Chen-LinYu, Huai-ChingTai, Juei-YuYen, Yu-LienTuan, Hsueh-Hsiao Wang, Yi-Ting Liu, Shiou-Sheng Chen, Hsueh-Yun Lee. Effect of phenylurea hydroxamic acids on histone deacetylase and VEGFR-2. BIOORGANIC & MEDICINAL CHEMISTRY. Vol.50:1-11. Nov. 2021. (SCI/SCIE)
- Chia-Chia Chao, Wei-Fang Lee , Shih-Wei Wang, Po-Chun Chen, Ayaho Yamamoto, Tsung-Ming Chang, Shun-Long Weng, Ju-Fang Liu. CXC chemokine ligand-13 promotes metastasis via CXCR5-dependent signaling pathway in non-small cell lung cancer. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. Vol.25-No.19:9128-9140. Oct. 2021. (SCI/SCIE)
- Kartiko Arif Purnomo, Michal Korinek , Yi-Hong Tsai , Hao-Chun Hu, Yi-Hsuan Wang, Anders Backlund, Tsong-Long Hwang, Bing-Hung Chen, Shih-Wei Wang, Chin-Chung Wu, Fang-Rong Chang . Decoding Multiple Biofunctions of Maca on Its Anti-allergic, Anti-inflammatory, Anti-thrombotic, and Pro-angiogenic Activities. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. Vol.69-No.40:11856-11866. Oct. 2021. (SCI/SCIE)
- Chien-Chung Huang, Yat-Yin Law, Shan-Chi Liu, Sung-Lin Hu, Jun-An Lin, Chao-Ju Chen, Shih-Wei Wang, Chih-Hsin Tang. Adiponectin Promotes VEGF Expression in Rheumatoid Arthritis Synovial Fibroblasts and Induces Endothelial Progenitor Cell Angiogenesis by Inhibiting miR-106a-5p. Cells. Vol.10-No.10:e2627. Oct. 2021. (SCI/SCIE)
- Ting-Kuo Chang, You-Han Zhong, Shan-Chi Liu, Chien-Chung Huang, Chun-Hao Tsai, Hsiang-Ping Lee, Shih-Wei Wang, Chin-Jung Hsu, Chih-Hsin Tang. Apelin Promotes Endothelial Progenitor Cell Angiogenesis in Rheumatoid Arthritis Disease via the miR-525-5p/Angiopoietin-1 Pathway. Frontiers in Immunology. Vol.12:e737990. Sep. 2021. (SCI/SCIE)
- Chun-Hao Tsai, Chao-Ju Chen , Chi-Li Gong, Shan-Chi Liu, Po-Chun Chen, Chien-Chung Huang, Sung-Lin Hu, Shih-Wei Wang, Chih-Hsin Tang. CXCL13/CXCR5 axis facilitates endothelial progenitor cell homing and angiogenesis during rheumatoid arthritis progression. Cell Death & Disease. Vol.12-No.9:e846. Sep. 2021. (SCI/SCIE)
- Chih-Yang Lin, Shih-Wei Wang, Jeng-Hung Guo, Huai-Ching Tai, Wen-Chun Sun, Cheng-Ta Lai, Chen-Yu Yang, Shih-Chia Liu, Yi-Chin Fong , Chih-Hsin Tang . WISP-3 Stimulates VEGF-C-Dependent Lymphangiogenesis in Human Chondrosarcoma Cells by Inhibiting miR-196a-3p Synthesis. Biomedicines. Vol.9(10):e1330. Sep. 2021. (SCI/SCIE)
- Hsien-Lin Chen, Yu-Chieh Su, Huang-Chi Chen, Jui-Hsin Su, Chang-Yi Wu, Shih-Wei Wang, In-Pin Lin, Chung-Yi Chen, Chien-Hsing Lee. Heteronemin Suppresses Lymphangiogenesis through ARF-1 and MMP-9/VE-Cadherin/Vimentin. Biomedicines. Vol.9-No.9:e1109. Aug. 2021. (SCI/SCIE)
- Shih-Ya Hung, Chih-Yang Lin, Cheng-Chieh Yu , Hsien-Te Chen, Ming-Yu Lien, Yu-Wen Huang, Yi-Chin Fong, Ju-Fang Liu, Shih-Wei Wang, Wei-Cheng Chen, Chih-Hsin Tang. Visfatin Promotes the Metastatic Potential of Chondrosarcoma Cells by Stimulating AP-1-Dependent MMP-2 Production in the MAPK Pathway. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Vol.22-No.16:e8642. Aug. 2021. (SCI/SCIE)
- Chien-Chung Huang, Tzu-Ting Tseng, Shan-Chi Liu, Yen-You Lin, Yat-Yin Law, Sung-Lin Hu, Shih-Wei Wang, Chun-Hao Tsai, Chih-Hsin Tang. S1P Increases VEGF Production in Osteoblasts and Facilitates Endothelial Progenitor Cell Angiogenesis by Inhibiting miR-16-5p Expression via the c-Src/FAK Signaling Pathway in Rheumatoid Arthritis. Cells. Vol.10-No.8:e2168. Aug. 2021. (SCI/SCIE)
- Wu SH, Hsieh CC, Hsu SC, Yao M, Hsiao JK, Wang SW, Lin CP, Huang DM*. RBC-derived vesicles as a systemic delivery system of doxorubicin for lysosomal-mitochondrial axis-improved cancer therapy.. Journal of Advanced Research. Vol.30:185-196. May. 2021. (SCI/SCIE)
- Shih-Wei Wang, Huai‐Ching Tai, Chih-Hsin Tang , Liang-Wei Lin, Tien-Huang Lin, An-Chen Chang, Po-Chun Chen, Yi-Hsuan Chen, Po-Chuan Wang, Yu-Wei Lai, Shiou-Sheng Chen. Melatonin impedes prostate cancer metastasis by suppressing MMP-13 expression. JOURNAL OF CELLULAR PHYSIOLOGY. Vol.236-No.5:3979-3990. May. 2021. (SCI/SCIE)
- Shu-Rong Chen, Shih-Wei Wang, Yu-Chi Lin, Chen-Lin Yu, Juei-Yu Yen, Yih-Fung Chen, Yuan-Bin Cheng. Additional alkaloids from Zoanthus vietnamensis with neuroprotective and anti-angiogenic effects. BIOORGANIC CHEMISTRY. Vol.109:e104700. Apr. 2021. (SCI/SCIE)
- Po-Chun Chen, Shan-Chi Liu, Tien-Huang Lin, Liang-Wei Lin, Hsi-Chin Wu, Huai-Ching Tai, Shih-Wei Wang, Chih-Hsin Tang. Prostate cancer-secreted CCN3 uses the GSK3β and β-catenin pathways to enhance osteogenic factor levels in osteoblasts. ENVIRONMENTAL TOXICOLOGY. Vol.36-No.3:425-432. Mar. 2021. (SCI/SCIE)
- Chen-Lin Yu, Meng-Shih Weng, Wei-Cheng Chen, Kai-Ting Chien, Chih-Wen Chi, Ching-Hu Chung, Chia-Wen Huang, Po-Chuan Wang, Chien-Chih Chen, An-Chi Tsai, Shih-Chia Liu, Shih-Wei Wang*. Moscatilin inhibits metastatic behavior of human hepatocellular carcinoma cells: a crucial role of uPA suppression via Akt/NF-κB-dependent pathway. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Vol.22-No.6:e2930. Mar. 2021. (SCI/SCIE)
- Hao-Chiun Chang, Shih-Wei Wang, Chin-Yen Chen, Tsong-Long Hwang, Ming-Jen Cheng, Ping-Jyun Sung , Kuang-Wen Liao, Jih-Jung Chen. Secoiridoid Glucosides and Anti-Inflammatory Constituents from the Stem Bark of Fraxinus chinensis. MOLECULES. Vol.25-No.5911:1-19. Dec. 2020. (SCI/SCIE)
- Lien MY, Chang AC, Tsai HC, Tsai MH, Hua CH, Cheng SP, Wang SW, Tang CH*. Monocyte Chemoattractant Protein 1 Promotes VEGF-A Expression in OSCC by Activating ILK and MEK1/2 Signaling and Downregulating miR-29c. Frontiers in Oncology. Vol.10-No.592415:1-11. Nov. 2020. (SCI/SCIE)
- Chen SR, Wang SW, Sheu JH, Chang TH, Cheng YB*. Zoanthamine Alkaloid Derivatives from the Zoantharian Zoanthus vietnamensis with Antimetastatic Activity. JOURNAL OF ORGANIC CHEMISTRY. Vol.85:12553-12560. Oct. 2020. (SCI/SCIE)
- Chang FR, Wang SW, Chen SR, Lee CY, Sheu JH, Cheng YB*. Aleuritin, a novel dinor-diterpenoid from the twigs of Aleurites moluccanus with an anti-lymphangiogenic effect. ORGANIC & BIOMOLECULAR CHEMISTRY. Vol.18:7892-7898. Oct. 2020. (SCI/SCIE)
- Chen WC, Lu YC, Kuo SJ, Lin CY, Tsai HC, Liu SC, Chen YL, Wang SW*, Tang CH*. Resistin enhances IL-1β and TNF-α expression in human osteoarthritis synovial fibroblasts by inhibiting miR-149 expression via the MEK and ERK pathways. FASEB JOURNAL. Vol.34:13671-13684. Oct. 2020. (SCI/SCIE)
- Chang TK, Wang YH, Kuo SJ, Wang SW, Tsai CH, Fong YC, Wu NL, Liu SC*, Tang CH*. Apelin enhances IL-1β expression in human synovial fibroblasts by inhibiting miR-144-3p through the PI3K and ERK pathways. Aging-US. Vol.12:9224-9239. Jun. 2020. (SCI/SCIE)
- Lin CL, Ying TH, Yang SF, Wang SW, Cheng SP, Lee JJ*, Hsieh YH* . Transcriptional Suppression of miR-7 by MTA2 Induces Sp1-Mediated KLK10 Expression and Metastasis of Cervical Cancer. Molecular Therapy-Nucleic Acids. Vol.20:699-710. Jun. 2020. (SCI/SCIE)
- Hsiao G, Wang SW, Chiang YR, Chi WC, Kuo YH, Phong DA, Chen CY, Lee TH*. Anti-inflammatory effects of peptides from a marine algicolous fungus Acremonium sp. NTU492 in BV-2 microglial cells. JOURNAL OF FOOD AND DRUG ANALYSIS. Vol.28:89-97. Jun. 2020. (SCI/SCIE)
- Chen JJ#, Wang SW#, Chiang YR, Pang KL, Kuo YH, Shih TY, Lee TH*. Highly Oxygenated Constituents from a Marine Alga-Derived Fungus Aspergillus giganteus NTU967. Marine Drugs. Vol.18(6):e303-e303. Jun. 2020. (SCI/SCIE)
- Chen WC, Lin CY, Kuo SJ, Liu SC, Lu YC, Chen YL, Wang SW*, Tang CH*. Resistin Enhances VCAM-1 Expression and Monocyte Adhesion in Human Osteoarthritis Synovial Fibroblasts by Inhibiting MiR-381 Expression Through the PKC, p38, and JNK Signaling Pathways. Cells. Vol.9(6):e1369-e1369. Jun. 2020. (SCI/SCIE)
- Tsai CH, Liu SC, Chung WH, Wang SW, Wu MH*, Tang CH*. Visfatin Increases VEGF-dependent Angiogenesis of Endothelial Progenitor Cells during Osteoarthritis Progression. Cells. Vol.9(5):e1315-e1315. May. 2020. (SCI/SCIE)
- Li CY, Chang CC, Tsai YH, Mohamed El-Shazly, Chin-Chung Wu, Shih-Wei Wang, Tsong-Long Hwang, Chien-Kei Wei, Judit Hohmann, Zih-Jie Yang, Yuan-Bin Cheng, Yang-Chang Wu, Fang-Rong Chang. Anti-inflammatory, Antiplatelet Aggregation, and Antiangiogenesis Polyketides from Epicoccum sorghinum: Toward an Understating of Its Biological Activities and Potential Applications. ACS Omega. Vol.5:11092-11099. May. 2020. (SCI/SCIE)
- Huang YW, Lin CY, Tsai HC, Fong YC, Han CK, Huang YL, Wu WT, Cheng SP, Chang HC, Liao KW, Wang SW*, Tang CH*.. Amphiregulin Promotes Cisplatin Chemoresistance by Upregulating ABCB1 Expression in Human Chondrosarcoma. Aging-US. Vol.12(10):9475-9488. May. 2020. (SCI/SCIE)
- Lai YW#, Wang SW#, Hu YY, Hwang TL, Cheng MJ, Chen IS, Sung PJ, Chen JJ*. Anti-inflammatory alkaloids from the root bark of Hernandia nymphaeifolia. PHYTOCHEMISTRY. Vol.173:e112326-e112326. May. 2020. (SCI/SCIE)
- Wang YH, Kuo SJ, Liu SC, Wang SW, Fong YC*, Tang CH*. Apelin Affects the Progression of Osteoarthritis by Regulating VEGF-Dependent Angiogenesis and miR-150-5p Expression in Human Synovial Fibroblasts. Cells. Vol.9(3):e594-e594. Mar. 2020. (SCI/SCIE)
- Wang SW, Lee CH, Lin MS, Chi CW, Chen YJ, Wang GS, Liao KW, Chiu LP, Wu SH, Huang DM*, Chen L*, Shen YS*. ZnO Nanoparticles Induced Caspase-Dependent Apoptosis in Gingival Squamous Cell Carcinoma Through Mitochondrial Dysfunction and p70S6K Signaling Pathway. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Vol.21(5):e1612-e1612. Feb. 2020. (SCI/SCIE)
- Wang SW, Lin MH, Hsu FC, Chen MC, Liou JP, Liu YT, Chen SS, Lee HY*. Synthesis and biological evaluation of 2-quinolineacrylamides. BIOORGANIC & MEDICINAL CHEMISTRY. Vol.28-No.3:1-9. Jan. 2020. (SCI/SCIE)
- Lee HP, Wang SW, Wu YC, Lin LW, Tsai FJ , Yang JS, Li TM, Tang CH*. Soya-cerebroside inhibits VEGF-facilitated angiogenesis in endothelial progenitor cells. FOOD AND AGRICULTURAL IMMUNOLOGY. Vol.31(1):193-204. Jan. 2020. (SCI/SCIE)
- Huang SW#, Yang HY#, Huang WJ, Chen WC, Yu MC, Wang SW, Hsu YF, Hsu MJ*. WMJ-S-001, a Novel Aliphatic Hydroxamate-Based Compound, Suppresses Lymphangiogenesis Through p38mapk-p53-survivin Signaling Cascade. Frontiers in Oncology. Vol.9-No.1188:1-16. Dec. 2019. (SCI/SCIE)
- Wang CQ, Lin CY, Huang YL, Wang SW, Wang Y, Huang BF, Lai YW, Weng SL, Fong YC, Tang CH, Lv Z. Sphingosine-1-phosphate promotes PDGF-dependent endothelial progenitor cell angiogenesis in human chondrosarcoma cells. Aging-US. Vol.11:11040-11053. Dec. 2019. (SCI/SCIE)
- Tsai HC, Cheng SP, Han CK, Huang YL, Wang SW, Lee JJ, Lai CT, Fong YC, Tang CH*. Resistin enhances angiogenesis in osteosarcoma via the MAPK signaling pathway. Aging-US. Vol.11:9767-9777. Nov. 2019. (SCI/SCIE)
- Hsu CC, Chao YY, Wang SW, Chen YL*. Polyethylenimine-capped silver nanoclusters as fluorescent sensors for the rapid detection of ellagic acid in cosmetics. TALANTA. Vol.204:484-490. Nov. 2019. (SCI/SCIE)
- Yang CY#, Chen C#, Lin CY, Chen YH, Lin CY, Chi CW, Chen YJ, Liu SC, Chang TK, Tang CH, Lai YW, Tsai HJ, Chen JJ*, Wang SW**. Garcimultiflorone K inhibits angiogenesis through Akt/eNOS- and mTOR-dependent pathways in human endothelial progenitor cells. PHYTOMEDICINE. Vol.64-No.152911:1-9. Nov. 2019. (SCI/SCIE)
- Chen SR, Wang SW, Chang FR*, Cheng YB*. Anti-Lymphangiogenic Alkaloids from the Zoanthid Zoanthus vietnamensis Collected in Taiwan. Journal of Natural Products. Vol.82:2790-2799. Oct. 2019. (SCI/SCIE)
- Lu CS, Lee YN, Wang SW, Wu YJ, Su CH, Hsieh CL, Tien TY, Wang BJ, Chen MC, Chen CW, Yeh HI*. KC21 Peptide Inhibits Angiogenesis and Attenuates Hypoxia-Induced Retinopathy. Journal of Cardiovascular Translational Research. Vol.12:366-377. Aug. 2019. (SCI/SCIE)
- Lee HP, Wang SW, Wu YC, Tsai CH, Tsai FJ, Chung JG, Huang CY, Yang JS, Hsu YM, Yin MC, Tang CH*. Glucocerebroside reduces endothelial progenitor cell-induced angiogenesis. FOOD AND AGRICULTURAL IMMUNOLOGY. Vol.30:1033-1045. Aug. 2019. (SCI/SCIE)
- Chang FR, Wang SW, Li CY, Lu YY, Liu SY, Chen CY, Wu YC, Cheng YB*. Natural Products from Diaporthe arecae with Anti‐Angiogenic Activity. Israel Journal of Chemistry. Vol.59:439-445. May. 2019. (SCI/SCIE)
- Tai HC, Lee TH, Tang CH, Chen LP, Chen WC, Lee MS, Chen PC, Lin CY, Chi CW, Chen YJ, Lai CT, Chen SS, Liao KW, Lee CH, Wang SW*. Phomaketide A Inhibits Lymphangiogenesis in Human Lymphatic Endothelial Cells. Marine Drugs. Vol.17(4):e215-e215. Apr. 2019. (SCI/SCIE)
- Li CY, Lo IW, Hseuh YP, Chung YM, Wang SW, Korinek M, Tsai YH, Cheng YB, Hwang TL, Wang CC, Chang FR*, Wu YC*. Epigenetic Manipulation Induces the Production of Coumarin‐Type Secondary Metabolite from Arthrobotrys foliicola. Israel Journal of Chemistry. Vol.59(5):432-438. Feb. 2019. (SCI/SCIE)
- Lee HP, Chen PC, Wang SW, Fong YC, Tsai CH, Tsai FJ, Chung JG, Huang CY, Yang JS, Hsu YM, Li TM, Tang CH*. Plumbagin suppresses endothelial progenitor cell-related angiogenesis in vitro and in vivo. Journal of Functional Foods. Vol.52:537-544. Feb. 2019. (SCI/SCIE)
- Chen SS#, Tang CH#, Chie MJ, Tsai CH, Fong YC, Lu YC, Chen WC, Lai CT, Wei CY, Tai HC, Chou WY, Wang SW**. Resistin facilitates VEGF-A-dependent angiogenesis by inhibiting miR-16-5p in human chondrosarcoma cells. Cell Death & Disease. Vol.10-No.31:1-13. Jan. 2019. (SCI/SCIE)
- Yu SY#, Wang SW#, Hwang TL, Wei BL, Su CJ, Chang FR*, Cheng YB*. Components from the Leaves and Twigs of Mangrove Lumnitzera racemosa with Anti-Angiogenic and Anti-Inflammatory Effects. Marine Drugs. Vol.16(11):e404-e404. Oct. 2018. (SCI/SCIE)
- Wei CY#, Wang SW#, Ye JW, Hwang TL, Chen MJ, Sung PJ, Chang TH, Chen JJ*. New Anti-Inflammatory Aporphine and Lignan Derivatives from the Root Wood of Hernandia nymphaeifolia. MOLECULES. Vol.23(9):e2286-e2286. Sep. 2018. (SCI/SCIE)
- Tzeng HE, Tang CH, Wu SH, Chen HT, Fong YC, Lu YC, Chen WC, Huang HD, Lin CY*, Wang SW**. CCN6-mediated MMP-9 activation enhances metastatic potential of human chondrosarcoma. Cell Death & Disease. Vol.9:e955-e955. Sep. 2018. (SCI/SCIE)
- Su CM#, Tang CH#, Chi MJ, Lin CY, Fong YC, Liu YC, Chen WC, Wang SW*. Resistin facilitates VEGF-C-associated lymphangiogenesis by inhibiting miR-186 in human chondrosarcoma cells. BIOCHEMICAL PHARMACOLOGY. Vol.154:234-242. Aug. 2018. (SCI/SCIE)
- Wang GS#, Shen YS#, Chou WY, Tang CH, Yeh HI, Wang LY, Yen JY, Huang TY, Liu SC, Yang CY, Lin TY, Chen C*, Wang SW**. Senescence Induces Dysfunctions in Endothelial Progenitor Cells and Osteoblasts by Interfering Translational Machinery and Bioenergetic Homeostasis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Vol.19(7):e1997-e1997. Jul. 2018. (SCI/SCIE)
- Wang SW, Chen YR, Chow JM, Chien MH, Yang SF, Wen YC, Lee WJ, Tseng TW. Stimulation of Fas/FasL-mediated apoptosis by luteolin through enhancement of histone H3 acetylation and c-Jun activation in HL-60 leukemia cells. Molecular carcinogenesis. Vol.57:866-877. Jul. 2018. (SCI/SCIE)
- Cheng LY, Chen CL, Kuo YH, Chang TH, Lin IW, Wang SW**, Chung MI*, Chen JJ*. Polyprenylated polycyclic acylphloroglucinol: Angiogenesis inhibitor from Garcinia multiflora. Bioorganic & Medicinal Chemistry Letters. Vol.28(10):1860-1863. Jun. 2018. (SCI/SCIE)
- Chen WC, Chung CH, Lu YC, Wu MH, Chou YC, Yen JY, Lai YW, Wang GS, Liu SC, Cheng JK, Wu YJ, Yeh HI, Wang LY, Wang SW*. BMP-2 induces angiogenesis by provoking integrin α6 expression in human endothelial progenitor cells. BIOCHEMICAL PHARMACOLOGY. Vol.150:256-266. Apr. 2018. (SCI/SCIE)
- Chung CH, Hsu CC, Lee AS, Wang SW, Lin KT, Chang WL, Peng HC, Huang WC, Chung CH*. 4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppression. BMC Complementary and Alternative Medicine. Vol.18-No.108:1-11. Mar. 2018. (SCI)
- Lien MY, Tsai HC, Chang AC, Tsai MH, Hua CH, Wang SW, Tang CH*. Chemokine CCL4 Induces Vascular Endothelial Growth Factor C Expression and Lymphangiogenesis by miR-195-3p in Oral Squamous Cell Carcinoma. Frontiers in Immunology. Vol.9:e412-e412. Mar. 2018. (SCI/SCIE)
- Chen SR#, Wang SW#, Su CJ, Hu HC, Yang YL, Hsieh CT, Peng CC, Chang FR*, Cheng YB*. Anti-Lymphangiogenesis Components from Zoanthid Palythoa tuberculosa. Marine Drugs. Vol.16(2):e47-e47. Mar. 2018. (SCI/SCIE)
- Lee HP, Liu YC, Chen PC, Tai HC, Li TM, Fong YC, Chang CS, Wu MH, Chiu LP, Wang CJ, Chen YH, Wu YJ, Tang CH*, Wang SW*. Tanshinone IIA inhibits angiogenesis in human endothelial progenitor cells in vitro and in vivo. Oncotarget. Vol.8:10921-10922. Dec. 2017. (SCI)
- Su SM, Wang IC, Liu SC, Sun Y, Jin L, Wang SW, Lee HP, Tseng WP, Tang CH*. Hypoxia induced mitogenic factor (HIMF) triggers angiogenesis by increasing interleukin-18 production in myoblasts. Scientific Reports. Vol.7-No.7393:1-11. Aug. 2017. (SCI)
- Lin CY#, Wang SW#, Chen YL, Chow WY, Lin TY, Chen WC, Yang CY, Liu SC, Hsieh CC, Fong YC, Wang PC*, Tang CH*. Brain-derived neurotrophic factor promotes VEGF-C-dependent lymphangiogenesis by suppressing miR-624-3p in human chondrosarcoma cells. Cell Death & Disease. Vol.8:e2964-e2964. Aug. 2017. (SCI/SCIE)
- Li CY, Lo IW, Wang SW, Hwang TL, Chung YM, Cheng YB, Tseng SP, Liu YH, Hsu YM, Chen SR, Hsu HC, Chang FR*, Wu YC*. Novel 11-norbetaenone isolated from an entomopathogenic fungus Lecanicillium antillanum(題目,附件,doi對不起來). Bioorganic & Medicinal Chemistry Letters. Vol.27:1978-1982. May. 2017. (SCI/SCIE)
- Tsai CH, Tseng HE, Huang CY, Huang YL, Tsai CH, Wang SW, Wang PC, Chang AC, Fong YC, Tang CH*. WISP-1 positively regulates angiogenesis by controlling VEGF-A expression in human osteosarcoma. Cell Death & Disease. Vol.8-No.2750:1-11. Apr. 2017. (SCI/SCIE)
- Wang LH, Tsai HC, Cheng YC, Lin CY, Huang YL, Tsai CH, Xu GH, Wang SW, Fong YC, Tang CH*. CTGF promotes osteosarcoma angiogenesis by regulating miR-543/angiopoietin 2 signaling. Cancer Letters. Vol.391:28-37. Apr. 2017. (SCI/SCIE)
- Li TM, Liu SC, Huang YH, Huang CC, Hsu CJ, Tsai CH, Wang SW, Tang CH*. YKL-40-Induced Inhibition of miR-590-3p Promotes Interleukin-18 Expression and Angiogenesis of Endothelial Progenitor Cells. International Journal of Molecular Sciences. Vol.18-No.920:1-14. Apr. 2017. (SCI)
- Chien MH, Lee TH, Lee WJ, Yeh YH, Li TK, Wang PC, Chen JJ, Chow JM, Lin YW, Hsiao M, Wang SW**, Hua KT*. Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts. Cancer Letters. Vol.388:249-261. Mar. 2017. (SCI/SCIE)
- Chen CY, Su CM, Hsu CJ, Huang CC, Wang SW, Liu SC, Chen WC, Fuh LJ*, Tang CH*. CCN1 Promotes VEGF Production in Osteoblasts and Induces Endothelial Progenitor Cells Angiogenesis by Inhibiting miR-126 Expression in Rheumatoid Arthritis. Journal of Bone and Mineral Research. Vol.32:34-45. Jan. 2017. (SCI/SCIE)
- Wang CQ, Huang YW, Wang SW, Huang YL, Tsai CH, Zhao YM, Huang BF, Xu GH, Fong YC, Tang CH*. Amphiregulin enhances VEGF-A production in human chondrosarcoma cells and promotes angiogenesis by inhibiting miR-206 via FAK/c-Src/PKCδ pathway. Cancer Letters. Vol.385:261-270. Jan. 2017. (SCI/SCIE)
- Lee MS, Wang SW, Wang GJ, Pang KL, Lee CK, Kuo YH, Cha HJ, Lin RK*, Lee TH*. Angiogenesis inhibitors and anti-inflammatory agents from Phoma sp. NTOU4195. Journal of Natural Products. Vol.79:2983-2990. Dec. 2016. (SCI/SCIE)
- Sun HL, Cui R, Zhou J, Teng KY, Hsiao YH, Nakanishi K, Fassan M, Luo Z, Shi G, Tili E, Kutay H , Lovat F, Vicentini C, Huang HL, Wang SW, Hung MC, Ghoshal K, Teng CM, Peng Y*, Croce CM*. ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5. Cancer Cell. Vol.30:723-736. Nov. 2016. (SCI/SCIE)
- Huang CY, Chang A, Chen HT, Wang SW, Lo YS, Tang CH*. Adiponectin promotes VEGF-C-dependent lymphangiogenesis by inhibiting miR-27b through a CaMKII/AMPK/p38 signaling pathway in human chondrosarcoma cells. Clinical Science. Vol.130:1523-1533. Sep. 2016. (SCI/SCIE)
- Tzeng HE, Chang AC, Tsai CH, Wang SW, Tang CH*. Basic fibroblast growth factor promotes VEGF-C-dependent lymphangiogenesis via inhibition of miR-381 in human chondrosarcoma cells. Oncotarget. Vol.7:38566-38578. Jun. 2016. (SCI)
- Yang WH, Chang AC, Wang SW, Wang SJ, Chang YS, Chang TM, Hsu SK, Fong YC, Tang CH*. Leptin promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-27b in human chondrosarcoma cells. Scientific Reports. Vol.6-No.28647:1-10. Jun. 2016. (SCI/SCIE)
- Chien SY, Huang CY, Tsai CH, Wang SW, Lin YM, Tang CH*. Interleukin-1β induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes. Clinical Science. Vol.130:667-681. May. 2016. (SCI/SCIE)
- Yeh YH, Wang SW, Yeh YC, Hsiao HF, Li TK*. Rhapontigenin inhibits TGF-β-mediated epithelial-mesenchymal-transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation. Oncology Reports. Vol.35:2887-2895. May. 2016. (SCI/SCIE)
- Wang LH, Lin CY, Liu SC, Liu GT, Chen YL, Chen JJ, Chan CH, Lin TY, Chen CK, Xu GH, Chen SS, Tang CH*, Wang SW*. CCL5 promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-507 in human chondrosarcoma cells. Oncotarget. Vol.7:36896-36908. May. 2016. (SCI)
- Tai HC*, Tai TY, Yang WS, Wang SW, Yu HJ. Associations between lower urinary tract dysfunction and glycemic control in women with type 2 diabetes: a cross-sectional study. Journal of Diabetes and Its Complications. Vol.30:415-419. Apr. 2016. (SCI)
- Lin CC, Chen PC, Lein MY, Tsao CW, Huang CC, Wang SW, Tang CH*, Tung KC*. WISP-1 promotes VEGF-C–dependent lymphangiogenesis by inhibiting miR-300 in human oral squamous cell carcinoma cells. Oncotarget. Vol.7:9993-10005. Mar. 2016. (SCI)
- Lai YW, Wang SW, Chang CH, Liu SC, Chen YJ, Chi CW, Chiu LP, Chen SS, Chiu AW, Chung CH*. Butein inhibits metastatic behavior in mouse melanoma cells through VEGF expression and translation-dependent signaling pathway regulation. BMC Complementary and Alternative Medicine. Vol.15-No.445:1-10. Dec. 2015. (SCI)
- Liao YY, Tsai HC, Chou PY, Wang SW, Chen CT, Lin YM, Chiang IP, Chang TM, Hsu SK, Chou MC, Tang CH, Fong YC. CCL3 promotes angiogenesis by dysregulation of miR-374b/VEGF-A axis in human osteosarcoma cells. Oncotarget. Vol.7:1-16. Dec. 2015. (SCI)
- Lee HP, Lin CY, Shih JS, Fong YC, Wang SW, Li TM, Tang CH. Adiponectin promotes VEGF-A-dependent angiogenesis in human chondrosarcoma through PI3K, Akt, mTOR, and HIF-α pathway. Oncotarget. Vol.6:36746-36761. Nov. 2015. (SCI)
- Su CM, Hsu CJ, Tsai CH, Huang CY, Wang SW, Tang CH. Resistin Promotes Angiogenesis in Endothelial Progenitor Cells Through Inhibition of MicroRNA206: Potential Implications for Rheumatoid Arthritis. Stem Cells. Vol.33:2243-2255. Jul. 2015. (SCI)
- Chen YL, Tsaur ML, Wang SW, Wang TY, Hung YC, Lin CS, Chang YF, Wang YC, Shiue SJ, Cheng JK. Chronic intrathecal infusion of mibefradil, ethosuximide and nickel attenuates nerve ligation-induced pain in rats. British of Anaesthesia. Vol.115:105-111. Jul. 2015. (SCI)
- Tzeng HE, Chen PC, Lin KW, Lin CY, Tsai CH, Han SM, Teng CL, Hwang WL, Wang SW, Tang CH. Basic fibroblast growth factor induces VEGF expression in chondrosarcoma cells and subsequently promotes endothelial progenitor cell-primed angiogenesis. Clinical Science. Vol.129:147-158. Jul. 2015. (SCI)
- Chuang JY, Chen PC, Tsao CW, Chang AC, Lein MY, Lin CC, Wang SW, Lin CW, Tang CH. WISP-1 a novel angiogenic regulator of the CCN family promotes oral squamous cell carcinoma angiogenesis through VEGF-A expression. Oncotarget. Vol.6:4239-4252. Feb. 2015. (SCI)
- Lin YH, Feng CH, Wang SW, Ko PY, Lee MH, Chen YL. Determination of Nicotine in Tobacco by Chemometric Optimization and Cation-Selective Exhaustive Injection in Combination with Sweeping-Micellar Electrokinetic Chromatography. Journal of Analytical Methods in Chemistry. Vol.869719:1-8. Feb. 2015. (SCI)
- Hsiao WY, Jiang SJ, Feng CH, Wang SW, Chen YL. Determining ultraviolet absorbents in sunscreen products by combining direct injection with micelle collapse on-line preconcentration capillary electrophoresis. Journal of Chromatography A. Vol.1383:175-181. Feb. 2015. (SCI)
- Lin GT, Huang YL, Tzeng HE, Tsai CH, Wang SW, Tang CH. CCL5 promotes vascular endothelial growth factor expression and induces angiogenesis by down-regulating miR-199a in human chondrosarcoma cells. Cancer Letters. Vol.357:476-487. Feb. 2015. (SCI)
- Wang SW, Liu SC, Sun HL, Huang TY, Chan CH, Yang CY, Yeh HI, Huang YL, Chou WY, Lin YM, Tang CH. CCL5/CCR5 axis induces vascular endothelial growth factor-mediated tumor angiogenesis in human osteosarcoma microenvironment. Carcinogenesis. Vol.36:104-114. Jan. 2015. (SCI)
- Yang WH, Chen JC, Hsu KH, Lin CY, Wang SW, Wang SJ, Chang YS, Tang CH. Leptin increases VEGF expression and enhances angiogenesis in human chondrosarcoma cells. Biochimica et Biophysica Acta - General Subjects. Vol.1840:3483-3493. Dec. 2014. (SCI)
- Liu SC, Chuang SW, Hsu CJ, Tsai CH, Wang SW, Tang CH. CTGF increases vascular endothelial growth factor-dependent angiogenesis in human synovial fibroblasts by increasing miR-210 expression. Cell Death and Disease. Vol.5-No.1485:1-12. Oct. 2014. (SCI)
- Lin CY, Hung SY, Chen HT, Tsou HK, Fong YC, Wang SW, Tang CH. Brain-derived neurotrophic factor increases vascular endothelial growth factor expression and enhances angiogenesis in human chondrosarcoma cells. Biochemical Pharmacology. Vol.91:522-533. Oct. 2014. (SCI)
- Tai HC, Chang AC, Yu HC, Huang CY, Tsai YC, Lai YW, Sun HL, Tang CH, Wang SW*. Osteoblast- derived WISP-1 increases VCAM-1 expression and enhances prostate cancer metastasis by down- regulating miR-126. Oncotarget. Vol.5:7589-7598. Sep. 2014. (SCI)
- Liu SC, Chen C, Chung CH, Wang PC, Wu NL, Cheng JK, Lai YW, Sun HL, Peng CY, Tang CH, Wang SW*. Inhibitory effects of butein on cancer metastasis and bioenergetics modulation. Journal of Agricultural and Food Chemistry. Vol.62:9109-9117. Sep. 2014. (SCI)
- Chen YL, Jiang SJ, Feng CH, Wang SW, Lin YH, Liu PY. Application of central composite design for the determination of exfoliating agents in cosmetics by capillary electrophoresis with electroosmotic flow modulation. Analytical Letters. Vol.47:1670-1682. Jun. 2014. (SCI)
- Chen JJ, Wang SW, Hsiao HY, Lee MS, Ju YM, Kuo YH, Lee TH. Aliphatic Phenolic Ethers from Trichobotrys effuse. Journal of Natural Products. Vol.77:1097-1101. May. 2014. (SCI)
- Hsiao CJ, Hsiao G, Chen WL, Wang SW, Chiang CP, Liu LY, Guh JH, Lee TH, Chung CL. Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption. Journal of Natural Products. Vol.77:758-765. Apr. 2014. (SCI)
- Chen PC, Cheng HC, Wang J, Wang SW, Tai HC, Lin CW, Tang CH. Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment. Oncotarget. Vol.5:1595-1608. Mar. 2014. (SCI)
- Wu MH, Huang CY, Lin JA, Wang SW, Peng CY, Cheng HC, Tang CH. Endothelin-1 promotes vascular endothelial growth factor-dependent angiogenesis in human chondrosarcoma cells. Oncogene. Vol.33:1725-1735. Mar. 2014. (SCI)
- Yu HS, Wang SW, Chang AC, Tai HC, Yeh HI, Lin YM, Tang CH. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochemical Pharmacology. Vol.87:243-253. Jan. 2014. (SCI)
- Lo HM, Wang SW, Chen CL, Wu PH, Wu WB. Effects of all-trans retinoic acid, retinol, and β-carotene on murine macrophage activity. Food & Function. Vol.5:140-148. Jan. 2014. (SCI)
- Chen-Ming Su, Shih-Wei Wang, Tzong-Huei Lee, Wen-Pei Tzeng, Che-Jen Hsiao, Shih-Chia Liu, Chih-Hsin Tang. Trichodermin induces cell apoptosis through mitochondrial dysfunction and endoplasmic reticulum stress in human chondrosarcoma cells. Toxicology and Applied Pharmacology. Vol.272:335-344. Oct. 2013. (SCI)
- Ching-Hu Chung, Chien-Hsin Chang, Shiou-Sheng Chen, Hsueh-Hsiao Wang, Juei-Yu Yen, Che-Jen Hsiao, Nan-Lin Wu, Yen-Ling Chen, Tur-Fu Huang, Po-Chuan Wang, Hung-I Yeh, Shih-Wei Wang*. Butein inhibits angiogenesis of human endothelial progenitor cells via the translation dependent signaling pathway. Evidence-Based Complementary and Alternative Medicine. Vol.943187:1-10. Jun. 2013. (SCI)
- Huey-En Tzeng, Chun-Hao Tsai, Zi-Ling Chang, Chen-Ming Su, Shih-Wei Wang, Wen-Li Hwang, Chih-Hsin Tang. Interleukin-6 induces vascular endothelial growth factor expression and promotes angiogenesis through apoptosis signal-regulating kinase 1 in human osteosarcoma. BIOCHEMICAL PHARMACOLOGY. Vol.85-No.4:531-540. Feb. 2013. (SCI/SCIE)
- Yen-Nien Chen, Tur-Fu Huang, Chien-Hsin Chang, Chun-Chieh Hsu, Kung-Tin Lin, Shih-Wei Wang, Hui-Chin Peng, Ching-Hu Chung. Antirestenosis Effect of Butein in the Neointima Formation Progression. Journal of Agricultural and Food Chemistry. Vol.60:6832-6838. Jun. 2012. (SCI)
- Shih-Wei Wang, Hsing-Hsien Wu, Shih-Chia Liu, Po-Chuan Wang, Wen-Chieh Ou, Wen-Yi Chou, Yung-Shuen Shen, Chih-Hsin Tang. CCL5 and CCR5 interaction promotes cell motility in human osteosarcoma. PLoS One. Vol.7-No.4:e35101. Apr. 2012. (SCI/SCIE)
- Tsai-Hua Chung, Jong-Kai Hsiao, Szu-Chun Hsu, Ming Yao, Yao-Chang Chen, Shih-Wei Wang, Mark Yen-Ping Kuo, Chung-Shi Yang, Dong-Ming Huang. Iron oxide nanoparticle-induced epidermal growth factor receptor expression in human stem cells for tumor therapy. ACS Nano. Vol.12:9807-9816. Dec. 2011. (SCI)
- An-Chi Tsai, Shiow-Lin Pan, Cho-Hwa Liao, Jih-Hwa Guh, Shih-Wei Wang, Hui-Lung Sun, Yi-Nan Liu, Chien-Chih Chen, Chien-Chang Shen, Ya-Ling Chang, Che-Ming Teng. Moscatilin, a bibenzyl derivative from the India orchid Dendrobrium loddigesii, suppresses tumor angiogenesis and growth in vitro and in vivo. Cancer Letters. Vol.292-No.2:163-170. Jun. 2010. (SCI/SCIE)
- An-Chi Tsai, Shiow-Lin Pan, Hui-Lung Sun, Chih-Ya Wang, Chieh-Yu Peng, Shih-Wei Wang, Ya-Ling Chang, Sheng-Chu Kuo, Kuo-Hsiung Lee, Che-Ming Teng. CHM-1, a new vascular targeting agent, induces apoptosis of human umbilical vein endothelial cells via p53-mediated death receptor 5 up-regulation. The Journal of Biological Chemistry. Vol.285:5497-5506. Feb. 2010. (SCI)
- Dong-Ming Huang, Jong-Kai Hsiao, Ying-Chun Chen, Li-Ying Chien, Ming Yao, Yin-Kai Chen, Bor-Sheng Ko, Szu-Chun Hsu, Lin-Ai Tai, Hui-Ying Cheng, Shih-Wei Wang, Chung-Shi Yang, Yao-Chang Chen. The promotion of human mesenchymal stem cell proliferation by superparamagnetic iron oxide nanoparticles. Biomaterials. Vol.30:917-925. Aug. 2009. (SCI)
- Shih-Wei Wang, Shiow-Lin Pan, Yu-Chun Huang, Jih-Hwa Guh, Po-Cheng Chiang, Der-Yi Huang, Sheng-Chu Kuo, Kuo-Hsiung Lee, Che-Ming Teng. CHM-1, a novel synthetic quinolone with potent and selective antimitotic antitumor activity against human hepatocellular carcinoma in vitro and in vivo. Molecular Cancer Therapeutics. Vol.7:350-360. Feb. 2008. (SCI)
- Shih-Wei Wang, Shiow-Lin Pan, Chieh-Yu Peng, Der-Yi Huang, An-Chi Tsai, Ya-Ling Chang, Jih-Hwa Guh, Sheng-Chu Kuo, Kuo-Hsiung Lee, Che-Ming Teng. CHM-1 inhibits hepatocyte growth factor-induced invasion of SK-Hep-1 human hepatocellular carcinoma cells by suppressing matrix metalloproteinase-9 expression. Cancer Letters. Vol.257-No.1:87-96. Nov. 2007. (SCI/SCIE)
- Ting-Chun Yeh, Po-Cheng Chiang, Tsai-Kun Li, Jui-Ling Hsu, Chun-Jung Lin, Shih-Wei Wang, Chieh-Yu Peng, Jih-Hwa Guh. Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult. BIOCHEMICAL PHARMACOLOGY. Vol.73-No.6:782-792. Mar. 2007. (SCI/SCIE)
- Shiow-Lin Pan, Jih-Hwa Guh, Chieh-Yu Peng, Shih-Wei Wang, Ya-Ling Chang, Fong-Chi Cheng, Jau-Hsiang Chang, Sheng-Chu Kuo, Fang-Yu Lee, Che-Ming Teng. YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models. Journal of Pharmacology and Experimental Therapeutics. Vol.314:35-42. Jul. 2005. (SCI)
- Shih-Wei Wang, Shiow-Lin Pan, Jih-Hwa Guh, Hui-Ling Chen, Dong-Ming Huang, Ya-Ling Chang, Sheng-Chu Kuo, Fang-Yu Lee, Che-Ming Teng. YC-1 [3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl Indazole] exhibits a novel antiproliferative effect and arrests the cell cycle in G0-G1 in human hepatocellular carcinoma cells. Journal of Pharmacology and Experimental Therapeutics. Vol.312:917-925. Mar. 2005. (SCI)
| 研討會 | - Shih-Wei Wang. CCL5 promotes vascular endothelial growth factor-dependent angiogenesis in human osteosarcoma. The 13th Annual Meeting of Japanese Society of Medical Oncology. Jul. 2015.
- Shih-Wei Wang*. Butein inhibits angiogenesis of human endothelial progenitor cells via the translation dependent signaling pathway. The 87th Annual Meeting of The Japanese Pharmacological Society. Mar. 2014.
- Shih-Wei Wang. CCL5/CCR5 axis promotes VEGF production in human osteosarcoma cells. Ninth AACR-JCA Joint Conference: Breakthroughs in Basic and Translational Cancer Research. Feb. 2013.
- Shih-Wei Wang*. CCL5 and CCR5 interaction promotes cell motility in human osteosarcoma. The 10th Annual Meeting of Japanese Society of Medical Oncology. Jul. 2012.
- Shih-Wei Wang*. Moscatilin inhibits invasion by suppressing urokinase plasminogen activator expression through Akt inactivation in human hepatocellular carcinoma cells. American Association for Cancer Research 102nd Annual Meeting. Apr. 2011.
| 計畫 | 計畫起訖年月 | 計畫名稱 | 擔任職務 |
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2023-08~2024-07 | 校外研究計畫獎助款(B)_MMC-RD-112-1B-P022_王士維 | 主持人 | 2022-08~2023-07 | 校外研究計畫獎助款(B)_MMC-RD-111-1B-P010_王士維 | 主持人 | 2022-08~2025-07 | 海洋真菌天然物抑制腫瘤血管新生之研究 | 主持人 | 2022-08~2023-07 | 探討螢光金奈米團簇在心血管疾病的作用機制及應用-螢光金奈米團簇在心衰竭對於心臟淋巴管新生之研究(3/3) | 主持人 | 2021-08~2022-10 | 中草藥活性成分抑制腫瘤淋巴管新生之研究(3/3) | 主持人 | 2021-08~2022-07 | 延攬博士後人才_尤振霖 | 主持人 | 2021-08~2022-07 | 校外研究計畫獎助款(B)_MMC-RD-110-1B-P015_王士維 | 主持人 | 2021-08~2022-07 | 探索中醫藥黃耆對癌症轉移的影響與治療應用(II)-Formononetin抑制腫瘤淋巴管新生及轉移之研究 | 主持人 | 2021-08~2022-07 | 探討螢光金奈米團簇在心血管疾病的作用機制及應用-螢光金奈米團簇在心衰竭對於心臟淋巴管新生之研究(2/3) | 主持人 | 2020-08~2021-07 | 螢光金奈米團簇在心衰竭對於心臟淋巴管新生之研究(3-1) | 主持人 | 2020-08~2021-07 | 中草藥活性成分抑制腫瘤淋巴管新生之研究(2/3) | 主持人 | 2020-08~2021-07 | 中草藥活性成分抑制腫瘤淋巴管新生之研究 | 主持人 | 2020-08~2021-07 | 延攬博士後人才_尤振霖 | 主持人 | 2020-08~2021-07 | 校外研究計畫獎助款(B)_1091B08_王士維 | 主持人 | 2020-08~2021-07 | 探索中醫藥黃耆對癌症轉移的影響與治療應用-黃耆活性成分抑制淋巴管新生之研究 | 主持人 | 2020-08~2021-07 | 探討螢光金奈米團簇在心血管疾病的作用機制及應用-螢光金奈米團簇在心衰竭對於心臟淋巴管新生之研究 | 主持人 | 2020-01~2020-12 | 新穎淋巴管新生抑制劑之探索 | 主持人 | 2019-08~2020-07 | 中草藥活性成分抑制腫瘤淋巴管新生之研究(1/3) | 主持人 | 2019-08~2020-07 | 108學年度管理費-總務處 | 主持人 | 2019-08~2020-07 | 中草藥活性成分抑制腫瘤淋巴管新生之研究 | 主持人 | 2019-08~2020-07 | 延攬博士後人才_林智暘 | 主持人 | 2019-08~2020-07 | 校外計畫獎助款_王士維_1081B32 | 主持人 | 2019-01~2025-07 | Phomaketide A在血管新生相關疾病之運用 | 主持人 | 2018-08~2019-07 | 新穎微型核糖核酸對於內皮起源細胞功能與相關血管疾病之調控(3/3) | 共同主持人 | 2018-08~2019-07 | 107學年度管理費-總務處 | 主持人 | 2018-08~2019-07 | 延攬博士後人才_林智暘 | 主持人 | 2018-08~2019-07 | 校外研究計畫獎助款_王士維_1071B27 | 主持人 | 2018-03~2018-04 | 106年度資收大學堂計畫 | 主持人 | 2018-01~2018-12 | MicroRNA-542-3p 在CCL5 調控人類骨肉瘤細胞doxorubicin 抗藥性之角色 | 主持人 | 2017-08~2018-07 | 新穎微型核糖核酸對於內皮起源細胞功能與相關血管疾病之調控(2/3) | 共同主持人 | 2017-08~2020-07 | 由天然物探索新穎之血管新生抑制劑 | 主持人 | 2017-08~2018-07 | 106學年度管理費-總務處 | 主持人 | 2017-08~2021-01 | 由天然物探索新穎之血管新生抑制劑 | 主持人 | 2017-08~2018-07 | 延攬博士後人才_林智暘 | 主持人 | 2017-08~2018-07 | 校外研究計畫獎助款_王士維
_1061B02 | 主持人 | 2016-08~2017-07 | 新穎微型核糖核酸對於內皮起源細胞功能與相關血管疾病之調控(1/3) | 共同主持人 | 2016-08~2017-07 | 探討CCL5調控骨肉瘤抗藥性之轉譯醫學研究 | 主持人 | 2016-08~2017-07 | 校外研究計畫獎助款_王士維
_1051B13 | 主持人 | 2016-08~2017-07 | 探討CCL5調控骨肉瘤抗藥性之轉譯醫學研究 | 主持人 | 2016-07~2017-02 | BMP-2在內皮起源細胞調控血管新生的作用與機轉-醫學系六年級周柏勳 | 主持人 | 2016-07~2017-02 | Butein 抑制淋巴管新生之作用與機轉-醫學系五年級林佾緯 | 主持人 | 2015-08~2016-07 | 探討miRNA在CCL5調控骨肉瘤抗藥性之角色及機轉 | 主持人 | 2015-08~2016-10 | 探討miRNA在CCL5調控骨肉瘤抗藥性之角色及機轉 | 主持人 | 2013-08~2016-07 | 探討內皮起源細胞之老化:強調機轉、預防以及心血管疾病的應用 | 共同主持人 | 2012-08~2015-07 | 探討CCL5調控骨肉瘤微環境之角色及機轉 | 主持人 | 2011-08~2012-07 | 探討CCL5調控骨肉瘤細胞轉移之角色及機轉 | 主持人 | 2010-08~2013-07 | 探討老化相關疾病之決定因素及機轉:強調粒線體失能的影響 | 共同主持人 |
| 專利 | 期間 | 專利名稱 | 證書號 | 發明人 |
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2018-04-01 ~ 2037-03-14 | 抑制血管新生之化合物及其製備方法 | I619706 | 湯智昕;李宗徽;王士維; | 2018-02-27 ~ 2038-02-27 | METHODS FOR TREATING ANGIOGENESIS RELATED DISORDER | US 10,561,637 B2 | Hsun-Shuo Chang;Ih-Sheng Chen;Chien-Jou Peng;Shih-Wei Wang;Chih-Hsin Tang; | 2015-12-28 ~ 2034-12-28 | AURANTIAMIDE DIPEPTIDE DERIVATIVES FOR TREATMENT OR PREVENTION OF ANGIOGENESIS-RELATED DISEASES | US 9,872,882 B2 | Hung-I Yeh;Shih-Wei Wang;Ching-Hu Chung;Pei-Wen Hsieh; |
| 編審 | 期間 | 期刊名稱 | 性質 |
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2017-03-24 ~ 2017-04-07 | Oncotarget | 審查委員 | 2017-02-26 ~ 2017-04-22 | International Journal of Medical Sciences | 審查委員 | 2017-01-02 ~ 2017-04-23 | Biomedicine & Pharmacotherapy | 審查委員 | 2016-12-01 ~ 2017-02-10 | Oncoatrget | 審查委員 | 2016-11-29 ~ 2016-12-03 | Adaptive medicine | 審查委員 | 2016-11-03 ~ 2016-11-28 | Scientific Reports | 審查委員 | 2016-10-04 ~ 2016-11-02 | Molecular Therapy-Nucleic Acids | 審查委員 | 2016-08-31 ~ 2016-09-14 | Oncotarget | 審查委員 | 2016-08-21 ~ 2016-08-29 | Oncotarget | 審查委員 | 2016-06-20 ~ 2016-07-02 | Journal of Agricultural and Food Chemistry | 審查委員 | 2016-06-17 ~ 2016-06-30 | Oncotarget | 審查委員 | 2016-06-16 ~ 2016-07-14 | Oncotarget | 審查委員 | 2016-04-20 ~ 2016-06-24 | PLoS One | 審查委員 | 2016-01-22 ~ 2016-01-24 | International Journal of Medical Sciences | 審查委員 | 2016-01-05 ~ 2016-01-14 | Oncotarget | 審查委員 | 2015-11-06 ~ 2015-11-24 | Adaptive Medicine | 審查委員 | 2015-08-26 ~ 2015-09-02 | Journal of Agricultural and Food Chemistry | 審查委員 | 2015-08-12 ~ 2015-09-22 | PLoS One | 審查委員 | 2015-04-22 ~ 2015-10-28 | Journal of Translational Medicine | 審查委員 | 2015-01-21 ~ 2015-02-14 | Journal of Agricultural and Food Chemistry | 審查委員 | 2015-01-13 ~ 2015-03-16 | BioMed Research International | 審查委員 | 2014-09-11 ~ 2014-11-10 | Journal of Agricultural and Food Chemistry | 審查委員 | 2014-07-24 ~ 2014-08-21 | BioMed Research International | 審查委員 | 2014-05-31 ~ 2014-06-21 | BioMed Research International | 審查委員 | 2014-01-01 ~ 2014-12-31 | PLoS One | 審查委員 | 2013-11-19 ~ 2013-12-18 | BioMed Research International | 審查委員 | 2012-01-01 ~ 2012-12-31 | International Journal of Gerontology | 審查委員 | 2009-10-01 ~ 2009-12-31 | British Journal of Pharmacology | 審查委員 |
| 榮譽 | 期間 | 榮譽名稱 | 舉辦國家 |
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2018-08-01 ~ 2019-07-31 | Special Outstanding Talent Award, Ministry of Science and Technology, 2018-2019. | Taiwan | 2017-10-13 ~ 2017-10-14 | 2017 中華天然藥物學會 優秀天然藥物學術論文獎 | Taiwan | 2017-08-01 ~ 2018-07-31 | Special Outstanding Talent Award, Ministry of Science and Technology, 2017-2018. | Taiwan | 2016-07-01 ~ 2017-02-28 | 科技部105年度 指導大專生研究計畫 榮獲研究創作獎 | Taiwan | 2014-08-01 ~ 2016-07-31 | Flexible Wage Award, Ministry of Education, 2014-2017. | Taiwan |
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個人興趣 |
團契活動、登山健行、旅遊、棒球
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聯絡方式 |
shihwei@mmc.edu.tw |
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