研究計畫

研究低密度膽固醇於心肌梗塞大鼠模式中的影響: 探討睡眠障礙與心律不整其作用機制

研究心臟衰竭之心血管自律神經調控與睡眠呼中止及心律不整的相關作用機制

研究腎臟動脈去神經於心肌梗塞大鼠中探討睡眠呼吸中止與心律不整的影響

研究心臟衰竭之心血管自律神經調控與睡眠呼中止及心律不整的相關作用機制

期刊論文發表

Tsai TY, Lo LW*, Liu SH, Cheng WH, Chou YH, Lin WL, Lin YJ, Chang SL, Hu YF, Chung FP, Liao JN, Chao TF, Lo MT, Yang HW, Chen SA. Delayed association of acute particulate matter 2.5 air pollution exposure with loss of complexity in cardiac rhythm dynamics: insight from detrended fluctuation analysis. Environ Sci Pollut Res Int. 2020 In press

Yamada S, Lo LW*, Chou YH, Lin WL, Chang SL, Lin YJ, Liu SH, Cheng WH, Tsai TY, Chen SA. Renal denervation ameliorates the risk of ventricular fibrillation in overweight and heart failure. Europace. 2020; 22:657-666. (SCI 4.045)

Yamada S, Lo LW*, Chou YH, Lin WL, Chang SL, Lin YJ, Liu SH, Cheng WH, Tsai TY, Chen SA. Renal denervation ameliorates the risk of ventricular fibrillation in overweight and heart failure. Europace. 2020; 22:657-666.

Huang TC, Lo LW*, Yamada S, Chou YH, Lin WL, Chang SL, Lin YJ, Liu SH, Cheng WH, Tsai TY, Liu PY, Chen SA. Gastroesophageal reflux disease and atrial fibrillation: Insight from autonomic cardiogastric neural interaction. J Cardiovasc Electrophysiol. 2019; 30(11):2262-2270.

Vicera JJB, Lo LW*, Yamada S, Chou YH, Lin YJ, Lo MT, Lin WL, Liu SH, Cheng WH, Tsai TY, Chen SA. Ultra-rapid high-density mapping system with the phase singularity technique is feasible in identifying rotors and focal sources and predicting AF termination. J Cardiovasc Electrophysiol. 2019; 30(6):952-963.

Tsai TY, Lo LW*, Liu SH, Cheng WH, Chou YH, Lin WL, Yamada S, Lin YJ, Chang SL, Hu YF, Chung FP, Liao JN, Chou TF, Tuan TC, Chen SA. Ambient fine particulate matter (PM2.5) exposure is associated with idiopathic ventricular premature complexes burden: A cohort study with consecutive Holter recordings. J Cardiovasc Electrophysiol 2019; 30(4):487-492.

Tsai TY, Lo LW*, Liu SH, Cheng WH, Chou YH, Lin WL, Lin YJ, Chang SL, Hu YF, Chung FP, Liao JN, Chao TF, Chen SA. Diurnal cardiac sympathetic hyperactivity after exposure to acute particulate matter 2.5 air pollution. J Electrocardiol 2019; 52:112-116.

Lin WL, Chen YR, Lai CT, Yamada S, Liu SH, Chou YH, Fu YC, Yang CCH, Kuo TBJ, Lo LW*, Chen SA. Neural mechanism of angiotensin-converting enzyme inhibitors in improving heart rate variability and sleep disturbance after myocardial infarction. Sleep Med. 2018; 48:61-69.

Chang HY, Lo LW*, Chen YR, Chou YH, Lin WL, Lin YJ, Yin WH, Feng AN, Chen SA. The autonomic neural mechanism of right ventricular outflow tract tachycardia. Auton Neurosci. 2018; 212:10-16.

Yamada S, Lo LW, Chou YH, Lin WL, Chang SL, Lin YJ, Chen SA*. Renal denervation regulates the atrial arrhythmogenic substrates through reverse structural remodeling in heart failure rabbit model. Int J Cardiol. 2017; 235:105-113.

Yamada S, Lo LW*, Chou YH, Lin WL, Chang SL, Lin YJ, Chen WH, Tsai TY, Chen SA*. Beneficial effect of renal denervation on ventricular premature complex induced cardiomyopathy. J Am Heart Assoc 2017;5: e004479 doi10.1161/JAHA.116.004479.

Lin WL, Lo LW*, Chen HR, Lai CT, Yamada S, Liu SH, Chou YH, Chen SA, Fu YC, Kuo Terry BJ*. Sleep-related changes in cardiovascular autonomic regulation in left coronary artery ligation rats: Neural mechanism facilitating arrhythmia after myocadial infarction. Int J Cardiol 2016; 225:65-72.

Chang HY, Lo LW*, Chou YH, Lin WL, Lin YJ, Yamada S, Chen SA. Effect of vagotomy on the activity of cardiac autonomic ganglia: Insight from left atrial high density frequency mapping. Int J Cardiol, 2016; 220;435-439.

Lo LW, Chang HY, Scherlag BJ, Lin YJ, Chou YH, Lin WL, Chen SA*, Po SS*. Temporary suppression of cardiac ganglionated plexi leads to long-term suppression of atrial fibrillation: Evidence of early autonomic intervention to break the vicious cycle of 'AF begets AF'. J Am Heart Assoc, 2016; 5:pii:e003309.

其他

The 12th Asia-Pacific Heart Rhythm Society Scientific Session 2018 (APHRS

2019). Bangkok, Thailand. Oct 24-27, 2019

Lecture: Effects of Renal Denervation to Cardiac Autonomics During Sleep in Rats

with Myocardial Infarction.

The 11th Asia-Pacific Heart Rhythm Society Scientific Session 2018 (APHRS

2018). Taipei, Taiwan. Oct 17-20, 2018

Lecture: Neural Mechanism of ACE Inhibitor in Improving Heart Rate

Variability and Sleep Disturbance after Myocardial Infraction.

Heart Rhythm 2018, the 39th Annual Scientific Sessions. Boston, USA. May 9-12,

2018.

Lecture: 1. Neural Mechanism of ACE Inhibitor in Improving Heart Rate

Variability and Sleep Disturbance after Myocardial Infarction.

2. Deep Sleep Stage Is Associated With Increased Risk Of Sudden

Cardiac Death After Myocardial Infarction: Insight From The

Preventive Effects Of ACE Inhibitor.

The 10th Asia-Pacific Heart Rhythm Society Scientific Session 2017 (APHRS

2017). Yokohama, Japan. Sep 14-17, 2017

Lecture: Neural Mechanism of ACE Inhibitor in Improving Heart Rate

Variability and Sleep Disturbance after Myocardial Infraction.

Heart Rhythm 2017, the 38th Annual Scientific Sessions. Chicago, USA. May 10-

13, 2017.

Lecture: Frequent Monomorphic VPCs Increased Fetal Arrhythmias through

Dysregulated Calcium Dynamics and Heterogeneous Microfibrosis

between Ventricles.

The 9th Asia-Pacific Heart Rhythm Society Scientific Session 2016 (APHRS

2016). Seoul, South Korea. Oct 12-15, 2016.

 Lecture: Fragmentation and Prolongation of Paradoxical Sleep Phase with

Sympathetic Hyperactivity in Left Coronary Artery Ligation Rats

Facilitates Fetal Arrhythmia and Sudden Death after Myocardial

Infarction.

The 8th Asia-Pacific Heart Rhythm Society Scientific Session 2015 (APHRS 2015)

In Conjunction with 11th Asia-Pacific Atrial Fibrillation Symposium 2015 (APAFS

2015). Melbourne, Australia, Nov19-22, 2015.

 Lecture: Sleep-Related Changes in Cardiovascular Autonomic Regulation in Left

Coronary Artery Ligation Rats: Neural Mechanism Facilitating Fetal

Arrhythmia after Myocardial Infarction.